A buddy of mine has a 392 hemi in his 32 Ford street rod and it's gone mid 10's in the quarter with low 3.xx gears in the rear end and a 727 automatic. It's a stock rebuilt bottom end with a supercharger. Certainly won't be cheap to build one but PAW has a catalog of parts just for the old hemi.
FWIW, the factory dual quad 392's were rated around 375-400 HP they were no slouches in stock form. Plus they were the basis for all top fuel dragsters for many years beyond the introduction of the 426 hemi.