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Keep it Simple...
There are only four engine tuning variables to keep in mind when dealing with nitrous oxide. They are:
Bottle Pressure – Bottle Pressure should be between 900-950 psi.
Fuel Pressure – As a general rule, do not exceed 6% fuel pressure drop when the nitrous system is activated. For example, if the OEM states that 45 psi is an acceptable fuel pressure for a given vehicle, the fuel pressure drop seen when the nitrous system is activated should be no more than 2.7 psi.
Timing – Retard ignition timing 1-1/2 ° to 2° for every 50 hp of nitrous used.
Spark Plugs – 1 heat range colder for every 100 hp, non-projected type plug with a gap of .025 to .035.

From the edlebrock website.