SB surgery. Have some ?s

I'm considering some updates/modifications to the 318 in my '71 Dart GT (with A904, MP electronic ignition (orange box), dual exhaust (factory manifolds, FlowMaster 40s, and 2 1/4" pipes to the rear bumper), 3.23:1 sure-grip 8 3/4" rear end).

I've got an Edelbrock LD4B intake manifold and an Edelbrock 1406 carburetor planned to go on this spring/summer.

While I'm at it I'm considering a Hughes whiplash cam/lifters/springs (all suggested by the folks at Hughes).
I also thought I should replace the timing chain/gears & water pump.

Can all of these modifications be made with the engine in the car?
What else would you all suggest?