Taking the air pump off the 318

So i am working on a mild rebuild on the dodge D100 pickup truck with 318 throttle body. I currently hooking all the connections back up on the motor. I am going to be running headers off the heads, and as i am hooking things back up I noticed that I really dont need the air pump and seen plenty of people run there cars with out it.

If I do not hook up anything off the air pump will the truck still run, and What would i do if there is a vaccum line that runs off the air pump to the throttle body how would I take care of that issue?

thanks for your guys help this my first rebuild so I am full of questions

Thanks