408 stroker with nitrous?
I recommend 10.5:1 compression with N2O. Cam needs to be around 110 lobe seperation you can choose lift and duration. Myself, I would get a custom ground cam for your specific combo. Cam ground will cost ya around $350.00. You will need to choose what system. We use Nitrous Express stuff. I like their plates. Get you a 1 gallon fuel cell and a Holley blue pump and mount these up front for the N2O setup. Tuning will be a challenge since it is for street use but just run 116 in the front cell. I like to run a tad rich on my tunes. Detonation will also destroy your investment if it ever runs lean. You will need a variety of "Pills" or jets for the plate. I usually run 3 sizes larger on the fuel side than the nitrous side. At the track we run 2 sizes larger on the fuel. Be sure to run 92-95 octane fuel in the main fuel tank.
This is my 2 cents on the matter. Some may have a different opinion! We setup the local boys chevys around here and have had no engine failures. Last one we did was a sbc 408 that runs 6.89 in the eighth on motor and 5.74 with 150 shot in a 3000lb S-10.
We also purge through the collectors so no one knows if they are spraying or not!!