My opinion (though nobody asked... lol) is that, if through some esoteric arrangement of parts in the reciprocating assembly, you could, somehow, build a 325 cubic slant 6 motor with a decent (1:1) bore stroke ratio, unless a free-flowing cylinder head (300 cfm, intake; 240 cfm, exhaust) can be fitted to this "wunderblock," it's never going to perform very well.
Horsepower is all about moving air... in this case. lots of it. I don't see ever getting it done, normally-aspirated, with a cylinder head that was designed to feed 170 cubic inches...
Just my 2-cents.:pain10: