Fish, I'm not familiar with E85, But i do think it requires more jet, but not as much as Alcohol, You could install small PVCRs & use the standard formula for gas as a base line, then just jet from there for best power, With those PVCRs being so large, it should still balance out useing the 67 jets from your calculations, Me personally would rather do like you said, run a smaller PVCR & larger jet, because the fuel will flow quicker into the main well through the jets then the PVChannels. I would installs .055"-.057" PVCR & start off with .080" jets & go from there.