Burnout....

Even a "mini-vacation" can ease the burn. Taking a break from your regular routine, get together with an old friend, go on a short hike someplace or toss a ball with some kids for a little while.

+1. Must take vacations with regularity to avoid burnout.

I used to work without taking vacations and most bosses don't really care. They don't look after you in terms of burnout so you need to look after yourself. You should take at least 2 or 3 vacations per year, even if you don't plan on going anywhere.