200-R4 transmission behind mopar stroker

I guess one of my concernes is that it might not hold up to my 416 stroker that I'm expecting to be in the 700hp range.. I've had a few pm's telling me not to waste my time b/c it wont hold up to the power level I'm wanting to be at. Most tell me to go withe the 4l80..for the price you get twice the transmission strength it looks like.. but how different is the preformance vs the 200r4? Is the 80 gear ratio from 1-2-3-4 good for drag and street duty compared to the 200?