The Most Powerful Small Block Mopar..??
If you can mix Nitro with the meth, I dont see why not. Fully ported W9 with that fuel combo, 15-16 to 1 compression, the right cam, the right intake(can you run dual carbs?)
4.200" bore, 3.79" stroke, 6.500" rod in a 48* block. Fully ported W9's will flow some air, 360-370cfm. Power would be in the 5000-9000rpm range
I hope you have deep pockets, this would be about a $40-50K USD build Im guessing.