Suggestions to reduce rust on water pump bolts?

Use a decent brand of anti-seize..... usually come's in a small plastic container with a brush. Permatex make's it, and several other's too. After wire wheeling the bolt's and thread's clean, just brush some anti-seize to the thread's and the bolt shank. Does not have to to put on heavy, just a liberal coat, and you will never have a problem with removing those bolt's again. Good luck.