318 stroker
Mike, while a 4" stroke engine with some compression can take a lot of cam. I can't think of any that would require a true idle of 1200+ that will work with the above quote? Cams like that just don't make the vacuum required to operate them properly on anything but a "show/fairgrounds" car. I'm pretty hardcore and have run PB's with 8/9" of vacuum before.....but it's not something I would ever recommend, even with a reserve tank.
I like where your basic thinking is with the combo, but the details of what you're using it for, and the rear gear you plan on running will help the discussion among most of us here.