5.7L hemi #6 Cylinder misfire

I had a similar problem on my 08 Dodge Ram 5.7 Hemi. The computer kept saying that I had a misfire on number 3 and 2 coil pack on number 3 cylinder. I was told that the lifter was the cause as well and that I needed it replaced. Or and I heard this also; flash the computer to turn the MDS off as well. I just didn't think that was the issue to be honest. So we took off all the coil packs and check the ohms and check and rechecked the plugs. Everything looked good. Put everything back together and again the same problem. I took the coil pack off that cylinder and changed it out for another one. Well the misfire went to the new cylinder we changed it too. So make a long story short. I thought it was a bad coil but ended up being the rubber boots that come off the coil was split and was causing the misfire against the inside of the head. Which was really annoying cause it ticked all the time too; since new. Put new boots all the way around and no more misfire and that tick is gone. I really never noticed much power lose just a miss when i was at idle. Worth checking out. Just my 2 cents.