Crossing state lines, with parts

I know dot laws are federal and I also know the moment they set foot into a (box) trailer it switches from looking to searching and that requires a warrant.

That's correct, they cannot "search" the load without a warrant (unless you are placarded for dangerous cargo). They "can" make you open the doors to inspect.

I see U-Haul trucks pulled over all the time, in multiple states, the reason is some small businesses will use them to transport their product without putting anything on the door etc. I see Penske trucks, Ryder trucks etc as well.

Federal law allows a DOT cop to pull you over if you're driving down the road with a ladder in the back of your truck. They think you might be going somewhere to perform work for someone for pay.

It's a nasty business dealing with them. When I started driving trucks 35 years ago it was nothing like it is now.