Sac would certainly be one of the best climates to run one. It really comes down to the intended use? I've been around, and tuned several dual carb street cars.....some worked ok, some would give me a complete headache :banghead:.
The main difference in my opinion was cam selection. That really is the determining factor for streetability. Torque converter, gearing, compression, etc. all have there place in choosing one, but the vacuum signal to the carbs is really what determines how the engine acts cruising around town.
P.S. Mounting the A/C compressor may be a bigger issue then getting her to run right. :D