From my 300C experience and the older Diablo tuners you could disable MDS with the tuner. You can of course install non-MDS lifters if you want to completely remove the system, but the heads need to come off to do that.
I am running a hotwire auto harness so hopefully leaving it disconnected will just be fine. If not, then I will have to have a diable tuned to disable it.
I do have replacement non mds lifters, valve springs etc but might save them for when I do a cam upgrade....
