10.5 compression on pump gas
I do 10.5 on PG all the time.
I'm in the process of 11.25 onPG with iron heads.
There are 2 things that matter. Cam timing and cooling system. If you try to run an off the shelf cam it will almost never work. If you call a COMPETENT cam company (preferably one who does NOT have a 6 digit advertising budget) and get a CUSTOM cam it will work.
FWIW I use (not in any particular order) Jim at Racer Brown, Cam Motion, and Mike Jones. I used to use UltraDyne when Brookshire owned it (now Bullet) but had issues with his constant idea of using lifts that were way too low and @.050 timing that way way too long.
But that is just me.