MRL Roller Lifter Street Durability

I'm not questioning the oil. I would still run the same zink additive that we
use in all of our flat tappet motors. I'm asking about the lifter durability.

What if I decide to go out and get on the interstate for a couple of hours?
Any problems to expect?

interested old man, I`ve got a set of them in my 505. sos far so good !