Misfire @ High RPM. Valve float or...???

sounds like , might be running out of fuel?? no volume!! ever time the pump?? see how long takes to pump a gallon of fuel? what size lines you have? filter.? other engine was smaller, right? you're trying to run a bigger engine with same fuel system from smaller engine. it can't feed the extra cubes!! you have to check every thing. fuel delivery is first place to start at. this is from mopar race.

X2

Correct springs?

Hydraulic lifters get unstable in that RPM range.