Supercharged or Stroked 360
I don't know about you guys, but if I saw a 408 stroker or blown 360 and it only made 400whp I'd be none too impressed. Not trying to insult anybody, but a well thought out 360 would meet that goal easily, IMO.
How about a stock stroke 360 in the 10-10.5:1 compression range, roller cam upgrade (spec'd for your build, there are a few advantages over flat tappet), ported aluminum heads(ported Eddys or Speedmaster), port matched intake (single or dual plane), and last but not least, EFI (FITECH is looking promising). A build like this would easily meet your goals and, IMO, would be much more enjoyable. No hassling with the blower setup. No having to worry about the longevity issues with a 4" stroke (Piston skirt wear). No fooling with stumbles, bogs, or heat soak issues associated with carbs (assuming you can tune one anyway). Just get in it, hit the key, and go.