Head Gasket Hole Sizing?

I've always use stock Felpro head gaskets but this time we are heading for some .045" thick Cometics. Our bore is 4.060" and we can get either 4.080" holes or 4.120" holes in the Cometics. (Or even 4.180".....) Is there a rule of thumb for how far back from the bore the head gasket's edge should be? I am thinking 4.125" holes, so any bore misalignment can be accomodated, but have never had to make this particular choice.