AEM EFI starting & tuning (Gen3 426)

I played with some AEM stuff years ago in college for a project, but I'm not 100% sure how the Mopar box is set up. For the most part, I think all the AEM ECUs are more or less "universal" boxes where the only real different is how many drivers it has in it for injectors/coils and the harness plug and pinout in the case of "plug and play" systems.

Reading over the responses so far I was thinking it sounds like the box shipped blank and required a base tune to be input, but it sounds like you might have that. If it's not firing spark or fuel I'd think it's probably a sync issue. I had all sorts of issues with that as I was adapting the setup I was working on to an engine with no cam and crank sensors. I found out my mounts weren't solid enough so my air gaps on the sensors were moving around and dropping signal. That shouldn't be an issue for you when using factory sensors, but you might see if you can watch a datalog of the cam and crank tooth count during engine cranking. If you're getting a solid tooth count then I'd double check all the channels are set up correctly for the injectors and coils and see if you can probe those plugs for power.