Radiators: Is 22" enough for 400 HP?

Not trying to be contrary at all but 4" is an 18% cooling increase... that ain't hay! Just some thoughts that might help you:

2) If that is not possible, event taking a 1" to 1.5" hole saw and putting extra holes along the edges of the rad opening in the core support may help a lot.

The hole saw idea for some reason sounds more appealing than cutting out the section of core support.

Anyway, I ended up purchasing a 26 inch 2 core radiator with 1 inch tubes. One reason for this is so I can do the Ford Contour fan mod. Seems to fit best on the 26 inch radiator.

I should have more pics up tomorrow. Today I worked on replacing my fuel sender.