carb issues

Have a problem with a holley 650 I just put on my 340. Car runs fine at idle, 1/4 throttle, and full throttle. It misses at 1/2 to 3/4 throttle. Hole shot is awesome. You cant hit the throttle fast enough to make it bog from an idle. Full out seems to be just as good as the 750 it replaced but throttle response is much better. Jets are 70 front and 77 rear without power valve in back. IT had 67 and 76s. The 70 jets helped but did no cure the miss. Should I keep going up or not. Seems like a big jump in jets to make it work.
car is 68 dart, 9.5 to 1 340 j heads 2.02 1.6 valves, rpm intake, and hughes cam. 237, 242 at .050 and 534,542 lift and 107 lsa. 3000 vert 3.55 gears. Cleaned carb very well. no plugged holes, floats set right. Please give me your thoughts. Thank you.