I have and have never had an issue with it. If your trying to run it in a car with cats though......no bueno.
I usually mix it 70/30 with 93 octane and have had great experiences.
Only problem is that if your out on a long trip, you have to plan ahead and either know where to buy more, or bring some with you.
Since I like to go on long cruises, I have been using Race-Gas for the last 3 years, and it works awesome. Never have any detonation problems and it mixes to whatever octane rating you desire, within their range.
It's about the same price as mixing Av Gas. I mix one 32 ounce can with 8-9 gallons of 93 pump gas and get 101 octane. It even smells just like racing fuel.
RACE GAS | Racing Fuel Concentrate
I have gone through at least 20 cans of this stuff and it's bullet proof.