Jamming in a big block?
For sure look-up the famous "Hemi Under Glass" Barracuda drag car of the 1960's. Several tribute cars have been fabb'ed.
I think all who have stuffed a BB or RB engine in an early-A had to route the headers thru cutouts in the inner fenders. Even 1967+ A's (wider) have had to do so. There were some factory BB cars later on. There is a "Big Block" forum here, plus an outside BigBlockDart.com website.
Many claim that exhaust is so restricted in a A that one can get faster 1/4 mile in a small-block. One guy even runs 10's w/ a turbo'ed slant six. For street driving or road racing, a big-block would be a lumbering beast on turns.