318 build with XE268 AND 302 heads

Key words zero-decked and 9.5 Scr. That will make a nice runner

And like nm9 says "headers would just add to everything".That cam wants headers to take advantage of the overlap cycle. Its only 52* but, with manifolds, the cycle is completely stifled. And that cycle begins working at about 2000rpm and increases effectiveness all the way to peak torque, and then to shift rpm.
If you are only gonna cruise it, with occasional power-bursts,then I wouldn't worry about it.
Combo looks good,especially if it pulls those 3.23s, with just a 2100TC. Very good.