6.1 Hemi into 72 Demon March 2018
Tr6060 is basically the same as a T56 magnum, at least externally. So yes, the upper crossmember will need significant modifications, a new mount and crossmember will need to be fabricated, and you’ll need to fabricate a new tunnel as well.
A member here does make a full replacement crossmember, he has a thread going here
Install a Tremec T56 Magnum in your A-body
There are a few member here that have done it, you can just search T56 swap to see what you’re up against.