Undersquare vs. Oversquare Engines

Here's food for thought; all are about 344 cubers, and all SBMs
4.06x3.315....3.91x3.58.....3.80x3.79.....3.70x4.00
Put the same small-valve heads on each of them, for obvious reasons.
Which would you rather have?
Well that depends on the application....right?
But optimize the valves and then what?