Rebuild Runs Rough

Yes ivc is at .050

I most likely had a winter e85 blend with the last engine. More gasoline, as much as 10% more. I probably have a more true e85 blend, now. I’m still able to trim fuel, I have full control, and its attitude feels right on my afr gauge. As I tune, and force a lean idle, the gauge goes towards 15:1 and beyond that it runs poorly, vacuum is reduced, as one would expect.
How does it run when you fatten it up?