Because of rod ratio, issues with feeding a 420 inch motor with available heads( without going exotic) the 3.79 stroke combo is probably the best option out there in many cases.
Less side loading, will rev better and higher more easily and intake port sizes commonly available are a better fit
For instance, even a well done W5 head on like say a 422 shortblock is “ one size to small” Been there, done that, seen that. With 4 inch or bigger tractor crank
I didnt like the fact Mopar 3.79 offerings were 1053, not 4340 forgings.
Think the 3.79 crank came out prior to any 4 inch stuff.
As well it probably should have, 3.79 arm suited W2/ W5 stuff better.
Talked to a lot of savvy smallblock guys over the years. Lot of them think the 3.79 deal is the way to go.