Ultimate home defence pistol?

Speaking of glock what is the best for a medium sized hand.
Wanting to do the 80%er build.


I carry a 27 every single day. If I buy another it will be the 29 as I'd like a 10mm to carry. I shoot 9mm worst of anything. Can't hit the broad side of a barn. That's why I carry the 27. I shoot .40 the best.