I am running the next cam up from Howards 260/264 on my stock stroke 360. Its roughly 10.3 compression and runs fine on pump premium but i most always run good stuff in it.
Stock 340 was 10.5 with iron head and ran fine on pump gas
Frankly i wouldnt quibble. 1/2 point in compression is maybe 1.5 percent more power. 10 horse maybe?. 10.5-7 compression would be a nice street goal
That cam sounds fine, smaller in a 4 inch motor than i would run on a healthy car, but not by much. I drive mine everywhere and race it a bunch. 4 inch stroke eats duration. Just depends how much you want to squeeze out more power