Depends on the tooling. If they are using carbide, they should be able to run it wide open and get "good" tool life.
No matter what they do, a Chrysler block and any aftermarket block will always be harder on tooling than anything else.
How do you think GM made their junk so cheap? Ultra soft blocks and heads so you can just smash the tooling through the material and things like open bolt holes (rather than blind like they should be) to make the junk as fast and cheap as they could.
And then there are things like compacted graphite cast iron.
That stuff is stupid hard and is hell on tooling. Great for power though.