Street Demon vs AVS2

My last engine was a 500 stroker, built with torque in mind, using a 750 Holley DP. My previous engine was a stock stroke 400 using an AFB. It was a very flexible street combination that made 450 ft/lbs of torque and 415 HP. The AFB ran well, but I hated the constant smell of gasoline in the garage as the fuel boiled out of the carburetor. The Holley solved that problem. I am now looking at building a slightly detuned version of the 400 I built, which will be easier for long distance cruising with a tall gear. I know there are trade offs, and I am not expecting Toyota mileage, but I think I can find a happy medium. Time will tell.