My understanding is this;
MSDs are MultiSpark
This type of system (Not MSD alone) are multi-strike systems below 3000-3600 because they have to be.
They just don't have enough amperage down there with one shot,to fire every big-cam,reversion-filled intake, lean burning, not quite right or just plain bad tune, out there. With just one shot the plug may; not ligh,not stay lit, or the fire kernel may not develop. So the hope is that the next or next or next or next or next and so on up to 10 sparks, will get the job done.
After the magic number of 3000 to 3500 whatever it was, there is no longer enough time for multiple sparks, and the amperage requirement of the mixture is falling, because the AF charge has stabilized, and all these combine in such a way that any old ignition that can deliver just one spark, but at just the right time.... will get the job done. Also,the faster you rev it, the less time between sparks. At 3600 rpm the dogone thing is firing; 3600/(60x every other revolution) =30 times per second, and you might as well just screw a glowplug into that hole. By 6000 it's 50 times per second.
Multistrike is not a feature; it's a failure hyped up to be a feature.
As for coils;
What you really want is an Accell P4120889 SuperCoil with it's matching P5206436 resistor. With that, you can idle your 292/108 equipped 360 down to 550rpm @5* advance, and still accelerate briskly away, then about 1500@18* advance you can stomp it, and the 750DP will reward you with instant tirespin thru the 4 speed and 3.55s or even 3.23 gears. In a pinch, I think you could use that coil as a welder; it lights every crap mixture you can imagine and never skips a beat, and it don't need no stinking multi-strike.
As for the ECUs.
ANY Mopar or jobber ECU will fire ANY system. You can rob an ECU off a 1980Volare 225 and stick it on your 71 360 in your 68 Barracuda, with a pirated 1973Dart harness,and expect to drive away. Now , they won't all rev to 7200, But you can drive 1000miles home and get you a proper box when you get there.
As for pick-ups
I believe in the Mopar Reluctor/ magnetic pick-up. Since 1971 when they came out, I have personally experienced exactly 1 pick-up failure. And in the crowd I hang with, I have never heard of another failure......... but I don't sell parts.
Yes some guys have experienced Orange-box failures, but not I.