To advance or Not
Check with Comp, a lot of their cams are ground with 4 degrees advance so straight up would be ok IMO, in Comp Cams install instructions it actually says its ok not to degree the cam but it is highly recommended, they also state to use the intake centerline method, but as others have stated it should be done to know where it is, how much difference you will see has to many variables to say for sure IMO but if you don't degree and aren't getting the performance you expected you will always wonder if it is an issue.