Safe to use Wheel Adapters 5 on 4" to 4.5"?

Not that particular pair. Those are cast, and have a tendency to crack because they're too thin.

Spacer/adaptors like that can be safe to use, but I would always use billet. The billet spacers are typically more like 1" thick, so using them for converting to BBP is problematic because of the backspace needed. Unless you're using 17" or larger wheels.

Like these
1" 1960s Mopar Chrysler 5x4 to 5x4.5 WHEEL Billet Adapters SAE 1/2x20 studs/nut | eBay
Thanks so If I did The 1ā€ Adaptors I will now need different backspacing on the rims right? I want to make sure I get the right rim size. Iā€™m doing 17ā€ rims in the front with 15ā€ in the back.