Safe to use Wheel Adapters 5 on 4" to 4.5"?

I wouldn't use wheel spacers or adapters of any kind.

They’re like anything else. Use good parts correctly and it will never be an issue.

Dually’s all use adaptors like that, and that’s heavy duty. An aluminum set of wheels is held onto the hub by what now? Right, the cast center of the wheel.

The cast adaptors don’t have enough material. But the billet adaptors are fine. Make sure all the nuts are torqued and check them at regular intervals (like you’re supposed to do for aluminum wheels!) and they aren’t an issue at all.