Horse power drop using early A 273 manifolds

I don't think so. I have an NOS 65 muffler and resonator. And I had a 65 Commando Maremount System around 1970 on my 64 Barracuda that had a straight through muffler and resonator for years. Maybe 65 had an intermediate pipe and muffler welded assy like the 67.
Ya, look it up. From what I have read, no muffler on the early cars. Way too loud so Ma Mopar added a muffler. May be @65dartcharger can clarify.