EFI and External Fuel Regulators

So, just browsing info on the different ways to set up EFI on these old dogs and I see that some are internally regulated (Sniper) and some aren't (Sniper Stealth). Is there any reason not to mount the regulator at the rear, in order to avoid taking the return line all the way to the front? I'm talking in-tank pump setups, something like a 'Tanks Inc' or Aerowhatever unit. With the pressurized fuel supply, as long as you get your desired pressure at the TB it should be fine, right? I haven't gotten real far into it at this point, perfectly content with carburetors, just wondering as an EFI may be in the future plans for my street beast--and I like the Stealth system and how it looks kinda like a carb.
Thanks