Compression ratio

I'm currently running 13:1 compression with my 408 on e85. The pistons are 5 thousands out of the hole with a 57cc Edelbrock head (ported). I also use Scat I-beams (great rod for the money). I have heard that you can go a little over 14:1 on e85...but I have no idea if you would have head gasket issues at that level (I'm using Felpro 1008's). My engine does seal up well with studs (also a good idea for high compression).

One thing you will need if you are going to run e85 is a wide-band O2 sensor. e85 burns so clean that it is VERY difficult to read plugs. The wide-band is about the only way to get a safe tune on the carb without guessing. I run my car between 0.77-0.82 lambda at WOT.

With that said, you can make pretty stupid power with the right setup....my Barracuda is running low 10's on e85 and can drive most anywhere...except past a gas station:D.
I'm currently running 13:1 compression with my 408 on e85. The pistons are 5 thousands out of the hole with a 57cc Edelbrock head (ported). I also use Scat I-beams (great rod for the money). I have heard that you can go a little over 14:1 on e85...but I have no idea if you would have head gasket issues at that level (I'm using Felpro 1008's). My engine does seal up well with studs (also a good idea for high compression).

One thing you will need if you are going to run e85 is a wide-band O2 sensor. e85 burns so clean that it is VERY difficult to read plugs. The wide-band is about the only way to get a safe tune on the carb without guessing. I run my car between 0.77-0.82 lambda at WOT.

With that said, you can make pretty stupid power with the right setup....my Barracuda is running low 10's on e85 and can drive most anywhere...except past a gas station:D.
My small block race motor ran reliably with 13-1 on alky in a dirt modified.

Mopar 340 rods and a Mopar billet steel crank. Stock parts are tuff enough that its unlikely you will break either.

The issues you will have with HIGH RPM is with the oiling system. Get that right and you are golden.
I greatly appreciate the great information flyfish. I am definitely going to be going with the Scat I-beams and studs for the mains and heads. Looking hard at the KB 167 pistons and will definitely go with wide-band O2 sensors. What carburetor are you running? Again I greatly appreciate the helpful information.