426 stroker dropped in scamp

I was wondering if it is safe to take a 340 or 360 out to 4.100 bore ?
340 I would but I personally don't build 360's. I've done everything I can to a 340. Got many spare blocks. Still waiting to run my heads and see if my math is ok and do some research & D with em on running motor. It will happen and 1 day be for sale.