The center 3 mains are the weakest, due to not being incorporated in the front and rear block walls , and the bottom shells do receive the most ponding.
If u think there is no stress on # 3 thrust bearing in a hemi or big block, why do they go south occasionally in hi h.p. , hooked up drag cars?
It was enough of a problem that the Chrysler drag seminars had some teaching on them back in the day . Most teams back then changed bearings on the prostock type cars regularly.
I lost a thrust bearing in a hemi s/s car once and learned of the problem from Tom Hoover.
Of course a lot if u younger guys probly don't even know who he was.
He was called the god father of the hemi.
Things have come a long way since then tho in engine and bearing design , I guess-----------