Is an 8 1/4", 2.45:1 diff housing exclusive?

The quick answer you need is yes, a 2.45 will not take another ratio.
the pinion is in a different spot in relation to the ring gear.
ask me how I know...

Finally after all the BULLSHIT somebody answered your question. Thanks, @motorpirate for being straight and to the point like no one else could.

To further the point, yes you do have other gear choices on the 2.45 carrier, but they are all numerically lower gearsets.......and there ARE a few. lol I think they go down to like 2.11 or some ridiculousness. But that's goin "the wrong way". LOL To upgrade with a numerically higher gearset, you will need another style carrier.