Bad intake Fuel/ air distribution or?

I have fixed a lot of tuning mistakes lately (learning from assuming things will work out of the box). Biggest change being that I had way too much mechanical timing (recently fixed by re curving the distributor) I also removed a MSD 6al after noticing a lot of timing walk at mid to high RPM (FBO in place now)
Admittedly through this I have been neglecting to keep up on reading all the plugs.
Pulled plugs tonight to see how things looked and noticed that the plugs from cylinders 1,2,5,7, and 8 are quite a bit richer than those pulled from 3,4 and 6. Any input on what I need to look at to get things balanced?
-Inake: Edelbrock performer
-Carb: Thermoquad
-Plugs: Champion RN12yc
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