Another "Is Fuel Injection a Worthwhile Upgrade?" Question
Firing up a new combination is just like anything else, it all depends on the details. If everything is assembled properly then an EFI setup will fire first crank. It isn't difficult to run thru a pre-start checklist.
We fire EFI engines on the dyno all the time without any issues. The drill is the same with carb or EFI. Spin the oil pump by hand to verify pressure and pre-oil the engine. Turn on the fuel pumps to verify pressure and check for leaks. Crank the engine by hand to verify rotor is pointing at #1 at 30 BTDC. Verify firing order on the engine matches the firing order on the cam card. Double check all connections. Spin it over and hit the ignition switch.