There are a few sensors that are not plug and play and must be swapped and re pinned. All of the wiring for the trans is different, as well as deleting all of the auto trans controls or using a manual ecu. Also the fuel systems between the two are different, including the injectors and fuel rails/regulator. Not entirely un doable but imo not worth the hassle. Especially if you have access to a buddy’s junkyard. Find a complete 2wd truck, and use everything from it. Engine, harness, pdc, ecu, and trans. If you do that it’s seriously like a 4 wire deal.