408 stroker 8-71 blower e85...teach me

Tried searching for a thread related to this topic but could not find one so I hope I am not creating another similar thread.

My question and the knowledge I am looking for is what should my static compression ratio be to run a roots blower on e85? How much boost can I run safely etc.
The build on the car and other info. I live in Colorado so high altitude.
The car is a 68 barracuda notch back. I will be stroking a 360 LA block to a 408. I have cage installed already and did inner fender delete and have glass fenders, hood and trunk lid. I am planning on running trick flow heads that are 190cc intake and the only options I see with these heads are 60cc chambers. Looks like ordering a scat forged rotating assembly with dished pistons at -20.5 cc I will be ranging a high compression ratio still. Looks like I made need to consider ordering custom dished pistons? At looking at some compression calculators running this scat kit with 62cc chambers that puts the compression ratio around 10.2:1. Obviously the 60cc chambers will be a higher compression ratio.
Has anyone done a build similar to this that the car is ran on e85 and is forced induction? With e85 being a higher octane rating than 91 octane. Is higher compression ok or is there still risk of too much compression and detonation?
I have tried reading up on this and find conflicting info. I have read in some other forums of people running higher compression with e85 and up to 35° in timing and others running lower compression with less timing. I just don't want to blow up the engine.
My dreams may be too much for reality. I'm not trying to make a pure race car. I am trying for best of both worlds. A cruiser that can fly on the street and a few trips to the track a year.
Still have to put in sub frame connectors and need to order magnum force front suspension w/ manual rack. Rear end planning on ordering moser fabricated rear end and running cal trac mono leaf and moving rear perches in.