fuel pressure dropping over time

Good point

It made 420 and change on the builders dyno

So your thinking is that even when it's clean it will restrict fuel flow?

I can see that, at full bore, but the pressure drop in seeing is during regular traffic
I don't recall you saying if it has ever worked properly. I would bypass or open up the regulator and give it a whirl. My son had a similar problem where his truck with a 360 would fall on its face after getting into it. We found the fuel pump was bad & after replacing it all is good again. When we took the pump out, the pump arm had slop in it.